Journal of Bone & Joint Surgery

Garrick W. Cason, MD1; Harry N. Herkowitz, MD2

Symptomatic adjacent-level disease after cervical fusion has led to the development and testing of several disc-replacement prostheses.

Randomized controlled trials of cervical disc replacement (CDR) compared with anterior cervical discectomy and fusion (ACDF) have demonstrated at least equivalent clinical results for CDR with similar or lower complication rates.